ORIGINAL RESEARCH ARTICLE: CERVIX AND HPV

2019 ASCCP Risk-Based Management Consensus

Guidelines for Abnormal Cervical Cancer Screening

Tests and Cancer Precursors

 

Table of Contents

SECTION

A. EXECUTIVE SUMMARY

B. INTRODUCTION

C. GUIDING PRINCIPLES

D. METHODS SUB-SECTION

D.1 Process and Timeline

D.2 Choice of CIN3+ as Main Clinical Endpoint for Risk Estimates

D.3 Multiple Data Sets Used to Validate Risks

D.4 Estimation of Risks

D.5 Assigning Combinations of Test Results to Clinical Actions

D.6 Rating the Recommendations

 

E. PARADIGM SHIFT: CLINICAL ACTION THRESHOLDS

E.1 Clinical Action Thresholds Leading to Recommendation of Surveillance

E.2 Clinical Action Threshold Leading to Recommendation of Colposcopy

E.3 Clinical Action Thresholds Leading to Recommendations of Treatment

E.4 Clinical Situations Leading to Management Recommendation

 

F. UPDATES RELATED TO PATHOLOGY REPORTING AND LABORATORY TESTS

F.1 Statement on the Use of a 2-Tier Terminology (Histologic LSIL/HSIL) for Reporting Histopathology of Squamous Lesions of the Lower Anogenital Tract

F.2 Updated Management of Primary HPV Screening (Replaces Interim Guidance)

F.3 Statement on HPV Tests Used in Management

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